Sebastián Airstrip (ICAO: SESB) is a small general aviation facility located in the Morona Santiago province of Ecuador, a region characterized by dense Amazonian rainforest and rugged terrain. The airstrip primarily serves local communities and light aircraft operations in an area where road access is limited or difficult. Morona Santiago is home to indigenous Shuar and Achuar communities, and small airstrips like this one play a vital role in connecting remote settlements to larger urban centers such as Macas, the provincial capital. Missionary aviation organizations and small charter operators historically have been among the primary users of such facilities in this region.